Commonly used inhaled narcotic drugs when using anesthesia machine

Views: 1687 Author: Site Editor Publish Time: 2021-03-05 Origin: Site

During the operation, in order to let the patient into the anesthetic state, the gas delivered to the patient's lung through the anesthesia system is called anesthetic gas. The commonly used anesthetic gas is enflurane, isoflurane, sevoflurane, desflurane, halothane, laughing gas, diethyl ether and so on.
  Enflurane
   For colorless transparent volatile liquid, no combustion, no explosion, taste airway no stimulation, chemical stability, sodium lime, UV does not decompose.
   Adverse Reactions and Precautions:
   1. Strong to breathing, circulation inhibition, should avoid deep anesthesia.
   2. It has mild inhibition of renal function and returns to normal soon after discontinuation. Severe kidney disease should be prohibited.
   3. Patients with epileptic pain and high intracranial pressure are contraindicated.
   Isoflurane
   It is an isomer of enflurane and its physical properties and pharmacological action are similar to that of enflurane
   The effect on cerebral blood flow is less than enflurane, and the effect on cerebral blood flow and intracranial pressure is adjusted by hyperventilation, so it can be used in craniocerebral surgery.
   Adverse reactions and precautions:
   1. When inhaled in high concentration, there is a concern of "coronary steal" due to coronary artery dilation.
   2. Deep anesthesia has the effect of inhibiting uterine contraction and increasing uterine bleeding, so it is not suitable for obstetric surgery.
   Sevoflurane
   It is a colorless liquid with pellucid fragrance, non-flammable, non-explosive and easy to preserve. Contact with sodium lime produces five substances
   The majority of sevoflurane inhaled is discharged through the lung, inducing and reviving faster than other fluorinated anesthetics, and causing no irritation to the respiratory tract, which has aroused great interest.
   Mask inhalation of 4% sevoflurane for 2 minutes can cause loss of consciousness.
   Inhibitory effect on respiration is dose-dependent, inducing comfortable and rapid, without causing cough and breath-holding. Can relax the bronchial smooth muscle, can be used for asthma patients.
   Adverse Reactions and Precautions:
   1. GP and GOT increased slightly after sevoflurane anesthesia, and recovered within a week. Therefore, severe liver and kidney diseases should be used with caution.
   2. Sevoflurane in contact with sodium lime produces five substances that are potentially toxic. Sodium lime should be replaced each time it is used to avoid too high temperature of sodium lime, and the concentration of sevoflurane inhalation should not be too high or the use of barium lime.
   3. It is forbidden to use general anesthesia within one month.
   Desflurane
   It is an inefficient inhaled anesthetic, non-flammable, non-explosive, and non-irritating to the airway. Induction and awakening very quickly. And in vivo biotransformation is very few, low toxicity, chemical stability, more and more people's attention.
   Inhibitory effect to central nervous system is related to dosage, suction 4 % - 11%, 2-4 minutes into surgical anesthesia period.
   Desflurane has little effect on circulatory function, so it is considered that desflurane is an almost ideal anesthetic for maintaining circulatory stability.
   Adverse Reactions and Precautions:
   1. It has mild irritation to respiratory tract and should be used with caution for induction in children.
   2. Desflurane boiling point is low, the use of electronic temperature control evaporator.
   Nitrous oxide (laughing gas)
   Colorless, non-irritating slightly sweet gas inhalation of the whole anesthetic, chemical stability, not combustion but combustible.
   The vast majority of nitrous oxide is excreted through the lungs, a small amount is dispersed through the skin, and only circulates in the form of physical dissolution in the plasma. In the condition of sufficient oxygen supply, the brain and heart. There were no adverse effects on liver and kidney.
   Anesthetic effect is relatively weak, inhalation of nitrous oxide 80% makes the consciousness hazy, inhalation of 30%-50% people have analgesic effect. Mixture with oxygen can reduce the MAC of the anesthetic by half.
   Nitrous oxide dilatation of cerebrovascular can increase intracranial pressure, but under sufficient oxygen supply, it has no effect on myocardial, heart rate, blood pressure, cardiac output and peripheral vascular resistance.
   Because it has no irritation to respiratory tract, it has no respiratory inhibition effect. But it can increase the suppression of respiration by other anesthetics. It is suitable for all kinds of operation, especially for severe shock and critical patients. Due to the weak efficacy of general anesthesia and high concentration of anoxia, it is often used as adjuvant drugs for general anesthesia, local anesthesia and intra-vertebral anesthesia and analgesia for induced abortion.

AMJ-560B3 and AMJ-560B5 are available to choose two kinds of gas from Halothane, Enflurane, Isoflurane, and Sevoflurane, ensuring a successful anesthesia operation. You can choose one of them to satisfy your demand.